OFFICES CLOSED

Due to inclement weather, all of our locations will be closed on Monday, January 26, 2026.

Stay safe!

  • photo of Trish dancing

    From 25th Street to

    Back on My Feet

    Pain-free and walking, Trish is grateful for Dr. Guse and the care he provided. To learn more about Dr. Cary Guse’s patient’s comeback story as well as other patient comeback stories, please use the button below.

    Learn More

    photo of Trish dancing

    From 
    25th Street to

    Back on My Feet

    Pain-free and walking, Trish is grateful for Dr. Guse and the care he provided. To learn more about Dr. Cary Guse’s patient’s comeback story as well as other patient comeback stories, please use the button below.

    Learn More

  • family walking in woods

    50 Years logo

    50 YEARS OF TRUSTED

    ORTHOPEDIC CARE

    Serving Southern Indiana Since 1976

    Learn More

    family walking in woods

    50 YEARS OF TRUSTED

    ORTHOPEDIC CARE

    Serving Southern Indiana Since 1976

    Learn More

  • family and dog

    THE REGION'S

    MOST PREFERRED*

    Serving the communities of southern Indiana for nearly 50 years, our team of specialty-trained providers is proud to use the strength of experience to make you stronger.

    family and dog

    THE REGION'S

    MOST PREFERRED*

    Serving the communities of southern Indiana for nearly 50 years, our team of specialty-trained providers is proud to use the strength of experience to make you stronger.

  • woman holding knee

    Orthopedic Urgent Care logo

    HURT TODAY?

    TREATED TODAY!

    Walk In and Be Seen for All Your Orthopedic Needs at Our Columbus Office

    Learn More

    woman holding knee

    HURT TODAY?

    TREATED TODAY!

    Walk In and Be Seen for All Your Orthopedic Needs at Our Columbus Office

    Learn More

  • online guides

    Your Online Guides to

    Orthopedic Care & Beyond

    We're here for your bone, joint, and muscle health journey. To help, we offer informative online guides on a variety of orthopedic topics for prevention, treatment options, and more.

    Access Our Guides

    online guides

    Your Online Guides to

    Orthopedic Care & Beyond

    We're here for your bone, joint, and muscle health journey. To help, we offer informative online guides on a variety of orthopedic topics for prevention, treatment options, and more.

    Access Our Guides

 Doctors

Our doctors are recognized experts in the diagnosis and treatment of orthopedic injuries and conditions.

 Specialties

We have the expertise, the experience, and the technology to provide exceptional orthopedic care dedicated to making you stronger.

 Locations

We provide services through four convenient locations throughout southern Indiana.

Welcome to Southern Indiana Orthopedics

Since 1976, Southern Indiana Orthopedics has remained dedicated to providing exceptional, experienced orthopedic care to make our patients and our community stronger. Focused on you, our board-certified and specialty-trained doctors deliver the treatment you need and the comprehensive care you deserve. 

As extensively trained and experienced specialists, we treat every bone, joint, and muscle concern. This includes highly specialized care for the ankleelbow, foot, hand, hip, knee, shoulder, and wrist. Out of our dedication to keeping you active, we also provide the latest in joint replacement and joint revision to renew the way you move as well as high-level sports medicine care to keep you in the game.

When you're ready to get stronger, see our specialists at any one of our convenient locations throughout southern Indiana, including our main office in Columbus and three outreach clinics in North Vernon, Seymour, and Greensburg.

Woman and young girl smiling

Patient Reviews

All the staff are very friendly. I would recommend this office to anyone needing orthopedic care.
– Angela L.
I received very professional and excellent care from Dr. Guse. It all went well, could not be happier with the experience.
– Sondra B.
Very professional and courteous.
– Carmelita M.
Recent left hip replacement great staff and doctor always has been honest and to the point with care.
– Merle M.
Had knee pain; went in for arthroscopy and 3 tears repaired; recovery went great almost pain free would recommend Dr. Guse for further problems.
– Susan W.